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Elise Camilleri

PhD Student

I hold a BSc in Astronomy from the University of Groningen and an MSc in Physics, specializing in Biological and Soft Matter Physics, from Leiden University. During my Master’s, I worked on two research projects: exploring breast cancer cell mechanics in the tumor microenvironment and investigating the effects of doxorubicin on chromatin folding using magnetic tweezers. These projects deepened my love for research and inspired me to pursue a PhD, leading me to join Kasia Tych’s lab.


My PhD project focuses on using single-molecule techniques to study how the molecular chaperone Hsp90 and its co-chaperones assist in folding two key client proteins: alpha-synuclein (AS) and the cystic fibrosis transmembrane regulator (CFTR). By using optical tweezers, mass photometry, and biochemical assays, I aim to better understand how Hsp90 affects the folding, stability, and interactions of these proteins, contributing to our understanding of neurodegenerative diseases and cystic fibrosis.

Elise Camilleri

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